Featured publications
Longitudinal gut virome analysis identifies specific viral signatures that precede necrotizing enterocolitis onset in preterm infants
May 1, 2022
Kaelin EA, Rodriguez C, Hall-Moore C, Hoffmann JA, Linneman LA, Ndao IM, Warner BB, Tarr PI, Holtz LR, Lim ES. Longitudinal gut virome analysis identifies specific viral signatures that precede necrotizing enterocolitis onset in preterm infants. Nat Microbiol. 2022 May;7(5):653-662. doi: 10.1038/s41564-022-01096-x. Epub 2022 Apr 21. PMID: 35449461; PMCID: PMC9064801.
Maternal obesogenic diet enhances cholestatic liver disease in offspring
May 1, 2022
Thompson MD, Hinrichs H, Faerber A, Tarr PI, Davidson NO. Maternal obesogenic diet enhances cholestatic liver disease in offspring. J Lipid Res. 2022 May;63(5):100205. doi: 10.1016/j.jlr.2022.100205. Epub 2022 Mar 25. PMID: 35341737; PMCID: PMC9046959.
Hematochezia in children with acute diarrhea seeking emergency department care – a prospective cohort study
April 1, 2022
Böhrer M, Fitzpatrick E, Hurley K, Xie J, Lee BE, Pang XL, Zhuo R, Parsons BD, Berenger BM, Chui L, Tarr PI, Ali S, Vanderkooi OG, Freedman SB; Alberta Provincial Pediatric EnTeric Infection TEam (APPETITE), Pediatric Emergency Research Canada (PERC). Hematochezia in children with acute diarrhea seeking emergency department care – a prospective cohort study. Acad Emerg Med. 2022 Apr;29(4):429-441. doi: 10.1111/acem.14434. Epub 2022 Feb 8. PMID: 34962688.
Maternal obesogenic diet regulates offspring bile acid homeostasis and hepatic lipid metabolism via the gut microbiome in mice
March 1, 2022
Thompson MD, Kang J, Faerber A, Hinrichs H, Özler O, Cowen J, Xie Y, Tarr PI, Davidson NO. Maternal obesogenic diet regulates offspring bile acid homeostasis and hepatic lipid metabolism via the gut microbiome in mice. Am J Physiol Gastrointest Liver Physiol. 2022 Mar 1;322(3):G295-G309. doi: 10.1152/ajpgi.00247.2021. Epub 2022 Jan 5. PMID: 34984925; PMCID: PMC8816615.
Alterations of host-gut microbiome interactions in multiple sclerosis
February 1, 2022
Cantoni C, Lin Q, Dorsett Y, Ghezzi L, Liu Z, Pan Y, Chen K, Han Y, Li Z, Xiao H, Gormley M, Liu Y, Bokoliya S, Panier H, Suther C, Evans E, Deng L, Locca A, Mikesell R, Obert K, Newland P, Wu Y, Salter A, Cross AH, Tarr PI, Lovett-Racke A, Piccio L, Zhou Y. Alterations of host-gut microbiome interactions in multiple sclerosis. EBioMedicine. 2022 Feb;76:103798. doi: 10.1016/j.ebiom.2021.103798. Epub 2022 Jan 27. PMID: 35094961; PMCID: PMC8814376.
Minimally Invasive Postmortem Intestinal Tissue Sampling in Malnourished and Acutely Ill Children Is Feasible and Informative
December 15, 2021
Feutz E, Voskuijl W, Finch PJ, Liu TC, Bandsma RHJ, Tarr PI, Moxon CA, VanBuskirk K, Lawrence S, Umutesi G, Tickell KD, Berkley JA, Walson JL, Kamiza S, Denno DM. Minimally Invasive Postmortem Intestinal Tissue Sampling in Malnourished and Acutely Ill Children Is Feasible and Informative. Clin Infect Dis. 2021 Dec 15;73(Suppl_5):S382-S389. doi: 10.1093/cid/ciab790. PMID: 34910181; PMCID: PMC8672761.
Recent publications
- Hyperhydration to Improve Kidney Outcomes in Children with Shiga Toxin-Producing E. coli Infection: a multinational embedded cluster crossover randomized trial (the HIKO STEC trial)On behalf of the Hyperhydration to Improve Kidney Outcomes in children with Shiga Toxin-producing E. Coli infection (HIKO-STEC) Study Team, Freedman, S. B., Schnadower, D., Estes, M., Casper, T. C., Goldstein, S. L., Grisaru, S., Pavia, A. T., Wilfond, B. S., Metheney, M., Kimball, K. & Tarr, P. I., Dec 2023, In: Trials. 24, 1, 359.Research output: Contribution to journal › Article › peer-review
- Study design and methods of the Wells and Enteric disease Transmission (WET) Trial: a randomised controlled trialLee, D., Denno, D., Tarr, P., Wu, J., Stokdyk, J. P., Borchardt, M. & Murphy, H. M., Mar 2 2023, In: BMJ Open. 13, 3, e068560.Research output: Contribution to journal › Article › peer-review
- Characterizing the Pain Experience of Children with Acute Gastroenteritis Based on Identified PathogensMa, K., Ali, S., Xie, J., Maki, C., Lee, B., Chui, L., Pang, X. L., Zhuo, R., Parsons, B., Vanderkooi, O., Poonai, N., Macdonald, S. E., Tarr, P. & Freedman, S. B., Feb 1 2023, In: Journal of pediatric gastroenterology and nutrition. 76, 2, p. 160-165 6 p.Research output: Contribution to journal › Article › peer-review
- Gut pathogen colonization precedes bloodstream infection in the neonatal intensive care unitSchwartz, D. J., Shalon, N., Wardenburg, K., DeVeaux, A., Wallace, M. A., Hall-Moore, C., Ndao, I. M., Sullivan, J. E., Radmacher, P., Escobedo, M., Burnham, C. A. D., Warner, B. B., Tarr, P. I. & Dantas, G., 2023, In: Science translational medicine. 15, 694, eadg5562.Research output: Contribution to journal › Article › peer-review
- Gut microbiome composition may be an indicator of preclinical Alzheimer’s diseaseFerreiro, A. L., Choi, J. H., Ryou, J., Newcomer, E. P., Thompson, R., Bollinger, R. M., Hall-Moore, C., Ndao, I. M., Sax, L., Benzinger, T. L. S., Stark, S. L., Holtzman, D. M., Fagan, A. M., Schindler, S. E., Cruchaga, C., Butt, O. H., Morris, J. C., Tarr, P. I., Ances, B. M. & Dantas, G., 2023, In: Science translational medicine. 15, 700, eabo2984.Research output: Contribution to journal › Article › peer-review