Featured publications
Longitudinal gut virome analysis identifies specific viral signatures that precede necrotizing enterocolitis onset in preterm infants
May 1, 2022
Kaelin EA, Rodriguez C, Hall-Moore C, Hoffmann JA, Linneman LA, Ndao IM, Warner BB, Tarr PI, Holtz LR, Lim ES. Longitudinal gut virome analysis identifies specific viral signatures that precede necrotizing enterocolitis onset in preterm infants. Nat Microbiol. 2022 May;7(5):653-662. doi: 10.1038/s41564-022-01096-x. Epub 2022 Apr 21. PMID: 35449461; PMCID: PMC9064801.
Maternal obesogenic diet enhances cholestatic liver disease in offspring
May 1, 2022
Thompson MD, Hinrichs H, Faerber A, Tarr PI, Davidson NO. Maternal obesogenic diet enhances cholestatic liver disease in offspring. J Lipid Res. 2022 May;63(5):100205. doi: 10.1016/j.jlr.2022.100205. Epub 2022 Mar 25. PMID: 35341737; PMCID: PMC9046959.
Hematochezia in children with acute diarrhea seeking emergency department care – a prospective cohort study
April 1, 2022
Böhrer M, Fitzpatrick E, Hurley K, Xie J, Lee BE, Pang XL, Zhuo R, Parsons BD, Berenger BM, Chui L, Tarr PI, Ali S, Vanderkooi OG, Freedman SB; Alberta Provincial Pediatric EnTeric Infection TEam (APPETITE), Pediatric Emergency Research Canada (PERC). Hematochezia in children with acute diarrhea seeking emergency department care – a prospective cohort study. Acad Emerg Med. 2022 Apr;29(4):429-441. doi: 10.1111/acem.14434. Epub 2022 Feb 8. PMID: 34962688.
Maternal obesogenic diet regulates offspring bile acid homeostasis and hepatic lipid metabolism via the gut microbiome in mice
March 1, 2022
Thompson MD, Kang J, Faerber A, Hinrichs H, Özler O, Cowen J, Xie Y, Tarr PI, Davidson NO. Maternal obesogenic diet regulates offspring bile acid homeostasis and hepatic lipid metabolism via the gut microbiome in mice. Am J Physiol Gastrointest Liver Physiol. 2022 Mar 1;322(3):G295-G309. doi: 10.1152/ajpgi.00247.2021. Epub 2022 Jan 5. PMID: 34984925; PMCID: PMC8816615.
Alterations of host-gut microbiome interactions in multiple sclerosis
February 1, 2022
Cantoni C, Lin Q, Dorsett Y, Ghezzi L, Liu Z, Pan Y, Chen K, Han Y, Li Z, Xiao H, Gormley M, Liu Y, Bokoliya S, Panier H, Suther C, Evans E, Deng L, Locca A, Mikesell R, Obert K, Newland P, Wu Y, Salter A, Cross AH, Tarr PI, Lovett-Racke A, Piccio L, Zhou Y. Alterations of host-gut microbiome interactions in multiple sclerosis. EBioMedicine. 2022 Feb;76:103798. doi: 10.1016/j.ebiom.2021.103798. Epub 2022 Jan 27. PMID: 35094961; PMCID: PMC8814376.
Minimally Invasive Postmortem Intestinal Tissue Sampling in Malnourished and Acutely Ill Children Is Feasible and Informative
December 15, 2021
Feutz E, Voskuijl W, Finch PJ, Liu TC, Bandsma RHJ, Tarr PI, Moxon CA, VanBuskirk K, Lawrence S, Umutesi G, Tickell KD, Berkley JA, Walson JL, Kamiza S, Denno DM. Minimally Invasive Postmortem Intestinal Tissue Sampling in Malnourished and Acutely Ill Children Is Feasible and Informative. Clin Infect Dis. 2021 Dec 15;73(Suppl_5):S382-S389. doi: 10.1093/cid/ciab790. PMID: 34910181; PMCID: PMC8672761.
Recent publications
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- Taking Microbiome Science to the Next Level: Recommendations to Advance the Emerging Field of Microbiome-Based Therapeutics and DiagnosticsBiotherapeutics Subcommittee of the AGA Center for Gut Microbiome Research and Education, Nov 2024, In: Gastroenterology. 167, 6, p. 1059-1064 6 p.Research output: Contribution to journal › Article › peer-review
- Clinical sequelae of gut microbiome development and disruption in hospitalized preterm infantsThänert, R., Schwartz, D. J., Keen, E. C., Hall-Moore, C., Wang, B., Shaikh, N., Ning, J., Rouggly-Nickless, L. C., Thänert, A., Ferreiro, A., Fishbein, S. R. S., Sullivan, J. E., Radmacher, P., Escobedo, M., Warner, B. B., Tarr, P. I. & Dantas, G., Oct 9 2024, In: Cell Host and Microbe.Research output: Contribution to journal › Article › peer-review
- Erratum: Clinical sequelae of gut microbiome development and disruption in hospitalized preterm infants (Cell Host & Microbe (2024) 32(10) (1822–1837.e5), (S1931312824002865), (10.1016/j.chom.2024.07.027))Thänert, R., Schwartz, D. J., Keen, E. C., Hall-Moore, C., Wang, B., Shaikh, N., Ning, J., Rouggly-Nickless, L. C., Thänert, A., Ferreiro, A., Fishbein, S. R. S., Sullivan, J. E., Radmacher, P., Escobedo, M., Warner, B. B., Tarr, P. I. & Dantas, G., Oct 9 2024, In: Cell Host and Microbe. 32, 10, p. 1868-1869 2 p.Research output: Contribution to journal › Comment/debate
- Histopathology underlying environmental enteric dysfunction in a cohort study of undernourished children in Bangladesh, Pakistan, and Zambia compared with United States childrenEEDBI Consortium, Sep 2024, In: American Journal of Clinical Nutrition. 120, p. S15-S30Research output: Contribution to journal › Article › peer-review
- Multiplexed immunohistochemical evaluation of small bowel inflammatory and epithelial parameters in environmental enteric dysfunctionEEDBI Consortium, Sep 2024, In: American Journal of Clinical Nutrition. 120, p. S31-S40Research output: Contribution to journal › Article › peer-review
- Duodenal transcriptomics demonstrates signatures of tissue inflammation and immune cell infiltration in children with environmental enteric dysfunction across global centersMarie, C., Das, S., Coomes, D., Ahmed, T., Ali, S. A., Iqbal, J., Kelly, P., Mahfuz, M., Moore, S. R., Petri, W. A., Tarr, P. I. & Denson, L. A., Sep 2024, In: American Journal of Clinical Nutrition. 120, p. S51-S64Research output: Contribution to journal › Article › peer-review
- The Environmental Enteric Dysfunction Biopsy Initiative (EEDBI) Consortium: mucosal investigations of environmental enteric dysfunctionEEDBI Consortium, Sep 2024, In: American Journal of Clinical Nutrition. 120, p. S4-S14Research output: Contribution to journal › Article › peer-review
- Anthropometry relationship with duodenal histologic features of children with environmental enteric dysfunction: a multicenter cross-sectional studyEEDBI Consortium, Sep 2024, In: American Journal of Clinical Nutrition. 120, p. S65-S72Research output: Contribution to journal › Article › peer-review
- Biomarker relationships with small bowel histopathology among malnourished children with environmental enteric dysfunction in a multicountry cohort studyEEDBI Consortium, Sep 2024, In: American Journal of Clinical Nutrition. 120, p. S73-S83Research output: Contribution to journal › Article › peer-review